Genetic determinants of voluntary exercise
نویسندگان
چکیده
منابع مشابه
Dopaminergic Genetic Variants and Voluntary Externally Paced Exercise Behavior.
PURPOSE Most candidate gene studies on the neurobiology of voluntary exercise behavior have focused on the dopaminergic signaling pathway and its role in the mesolimbic reward system. We hypothesized that dopaminergic candidate genes may influence exercise behavior through additional effects on executive functioning and that these effects are only detected when the types of exercise activity ar...
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Background. Previous surveys have shown that motor deficits precede the classical motor symptoms seen in Parkinson’s disease (PD) and that physical exercise may have beneficial effects on PD. Objectives. Here, we evaluated the potential of voluntary exercise to improve motor deficit in experimentally-induced Parkinson’s disease (6-OHDA) rats. Methods. Forty adult Wistar rats were ...
متن کاملGenetic architecture of voluntary exercise in an advanced intercross line of mice.
Exercise is essential for health, yet the amount, duration, and intensity that individuals engage in are strikingly variable, even under prescription. Our focus was to identify the locations and effects of quantitative trait loci (QTL) controlling genetic predisposition for exercise-related traits, utilizing a large advanced intercross line (AIL) of mice. This AIL (G(4)) population originated f...
متن کاملInfluence of voluntary exercise on hypothalamic norepinephrine.
We combined hypothalamic tissue and plasma determinations of norepinephrine, dihydroxyphenylalanine, and dihydroxyphenylglycol with measurements of abdominal fat in voluntary running rats to examine the relationship among exercise training, hypothalamic and sympathetic nervous function, and body fat stores. The hypothalamic concentrations of norepinephrine, dihydroxyphenylalanine, and dihydroxy...
متن کاملA transdisciplinary model integrating genetic, physiological, and psychological correlates of voluntary exercise.
OBJECTIVE Physical inactivity contributes to as many as 250,000 premature deaths per year (R. R. Pate et al., 1995). The authors' objective was to test a transdisciplinary model of the ways in which genetic variants, physiological factors, and psychological factors are thought to influence exercise with 64 healthy, regular exercisers. DESIGN In a within-subjects design, psychological and phys...
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ژورنال
عنوان ژورنال: Trends in Genetics
سال: 2013
ISSN: 0168-9525
DOI: 10.1016/j.tig.2012.12.007